Study on the expression of soluble Fas in the placenta of pregnancy induced hypertension (PIH) patients by fluorescent MGB probe real-time PCR
10.3760/cma.j.issn.1008-6706.2010.22.022
- VernacularTitle:荧光MGB探针检测妊娠期高血压疾病患者分娩后胎盘sFas表达研究
- Author:
Qi SHEN
;
Zhi ZHANG
;
Xiaomei ZHOU
- Publication Type:Journal Article
- Keywords:
Hypertension pregnancy- induced;
Soluble Fas(sFas);
In situ hybridization,fluorescence
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(22):3066-3068
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the the expression of soluble Fas (sFas) in the placenta of pregnancy induced hypertension (PIH) patients after perinatal. Methods Expression of sFas were detected by Fluorescent MGB Probe Real-Time PCR in 34 severe PIH patients and 30 healthy pregnant women served as normal controls.Results Expression of placenta sFas in 34 patients were significantly higher than those in normal controls.Conclusion PIH patients' placenta had higher expressiom of sFas; Detection of sFas may be helpful to value PIH degrade and sFas would be become a indicative markers of cell proliferation and apoptosis during the perinatal period.
