The seroimmunological analysis of 117 multiple myeloma cases in xinjiang

VernacularTitle:多发性骨髓瘤117例血清免疫学特征分析
Author: Huixia MA ; Shuying FAN ; Shuli GUO
Publication Type:Journal Article
Keywords: Multiple myeloma; Blood protein electrophoresis; Immunoelectrophoresis
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(22):3073-3074
CountryChina
Language:Chinese
Abstract: Objective To analyze the immunological feature of the multiple myeloma. Methods The serum of 117 cases were detected by serum protein electrophoresis and immunofixation electrophoresis;and analyzed quantitatively immune globulin(IgG、IgA、IgM) ,total protein and albumin. Results Monoclone protein peak was found in 67 patients out of 117 patients tested(57.3%) ,it located mainly at γ border. Immunoglobulin G was found in 62 patients out of 117 patients tested(53.0%). Immunoglobulin A was 19 cases(16.3%) ,Immunoglobulin M was 12 cases(10. 1%) ,DL was 2 cases(1.7%) ,free light chain was 22 cases(18.8%). Homotypic immunoglobulin level increased notably and non-correspond constituent was low in immunoglobulin test. The protein quantified displayed that total protein increased and albumin decreased in different level. Conclusion The seroimmunological index played a crucial role in diagnois,clinical stage and prognosis of MM.