Serum uric acid and prehypertension among Chinese adults

VernacularTitle:中国成年人血清尿酸与高血压前期的关系
Author: Fei TENG ; Jun HANG ; Caiyan ZOU ; Lu QI ; Huaidong SONG
Publication Type:Journal Article
Keywords: Uric acid; Hypertension; Epidemiology
From: Chinese Journal of Internal Medicine 2010;49(11):921-924
CountryChina
Language:Chinese
Abstract: Objective The aim of this article is to discuss the relation between serum uric acid and prehypertension, and to evaluate the influence of age, obesity, fasting plasma glucose (FPG) and lipids in Chinese adults. Methods All the 14 451 non-hypertensive samples were analyzed for blood pressure, body mass index (BMI), FPG, lipids and serum uric acid. Results The serum uric acid levels were stratified by quintiles, after adjustment for relevant factors, OR values of prehypertcnsion increased with the elevated uric acid levels. Serum uric acid level was 200-380 μmol/L, it had a linear relationship with the risk of prehypertension, 200 μmol/L as a turning point for this linear relationship, FPG could affect their correlation (P ＜ 0.0001 ). Conclusions Serum uric acid was associated with prehypertension, independent of metabolic risk factors. The associations were not significant in old individuals. FPG may modify the associations.