IL-17 and kidney diseases
10.3760/cma.j.issn.1673-4408.2010.06.032
- VernacularTitle:白细胞介素17与肾脏疾病的关系
- Author:
Kexin SHUAI
- Publication Type:Journal Article
- Keywords:
Interleukin 17;
Kidney disease;
Cytokine
- From:
International Journal of Pediatrics
2010;37(6):645-647
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin 17(IL-17) is a novel member of potent proinflammatory cytokines secreted by Th17 cell subset. It plays an important role in inflammatory and autoimmune diseases due to its specific biological functions. This paper reviews the structure and coding gene, biological functions of IL-17, and association with kidney diseases as well. Further studies on the role of IL-17 in kidney diseases will help the understanding about their pathogenesis as well as the search for new treatment targets to these diseases.