Observation on clinical therapeutic effect of Alprostadil combined with Magnesium Isoglycyrrhizinate on patients with Hepatocirrhosis at active phase

VernacularTitle:前列地尔联合异甘草酸镁治疗肝硬化活动期疗效观察
Author: Hong LI ; Yuan HE ; Ming WEI ; Rui HE
Publication Type:Journal Article
Keywords: Alprostadil; Glycyrrhizic acid; Liver cirrhosis
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(22):3068-3069
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effect of Alprostsdil combined with Magnesium Isoglycyrrhizinate on hepatocirrhosis at active phase. Method 74 inpatients collected from our hospital were randomly divided into control group(37 cases)and treatment group(37 cases). The patients in control group were given conventional liver protecting treatment. In addition to routine therapy of the control group, the patients in treatment group received intravenous Alprostadil and Magnesium Isoglycyrrhizinate injection once a day for 4 weeks. Results The total effective rate of treatment group was 67. 6%, and that of control group was 40. 5%, and the difference was significant (P ＜ 0. 05).Conclusion Alprostadil combined with Magnesium Isoglycyrrhizinate has good clinical therapeutic effect on hepatocirrhosis at active phase.