The Role of Radiation Therapy in Adenocarcinoma of Endometrium.
- Author:
Hyong geun YUN
1
;
Sung Whan HA
;
Soon Beom KANG
;
Hyo Pyo LEE
Author Information
1. Department of Therapeutic Radiology, College of Medicine Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Radiation therapy;
Adenocarcinoma of endometrium
- MeSH:
Adenocarcinoma*;
Diabetes Mellitus;
Endometrial Neoplasms;
Endometrium*;
Female;
Humans;
Hypertension;
Korea;
Menopause;
Multivariate Analysis;
Neoplasm Metastasis;
Obesity;
Parity;
Radiotherapy;
Seoul;
Survival Rate
- From:Journal of the Korean Society for Therapeutic Radiology
1990;8(1):95-102
- CountryRepublic of Korea
- Language:English
-
Abstract:
From May, 1979 to October, 1987, 38 patients with endometrial carcinoma were treated with radiotherapy at Seoul National University Hospital. Of these, 32 patients received radiotherapy postoperatively, one received radiotherapy preoperatively, and five received radiotherapy only. Relative frequencies of obesity, nulliparity, late menopause, diabetes mellitus and hypertension were all higher than those reported in normal women in Korea, and those of obesity, diabetes mellitus, and nulliparity were significantly high. The overall actuarial five-year survival rate was 75.6%. The overall actuarial five year survival rates of stage I(22 cases), stage II(six cases), and stage III(10 cases) were 90.0%, 80.0%, and 44.4%, respectively, and were significantly different from each other. Among various factors, stage only proved to be prognostic by multivariate analysis. There were two local failures, three local failures combined with distant metastasis, and three distant metastasis. Stages Iand II could be adequately controlled by local modalities without severe complications, stage III endometrial carcinoma might need more aggressive treatment for better survival.
