Risk factors associated with the progression of vitiligo

VernacularTitle:白癜风进展相关危险因素分析
Author: Liangjun LU ; Aie XU ; Cuiping GUAN ; Meihua CHEN
Publication Type:Journal Article
From: Chinese Journal of Dermatology 2011;44(1):52-54
CountryChina
Language:Chinese
Abstract: Objective To analyse the possible risk factors associated with the progression of vitiligo.Methods A questionnaire survey was carried out to collect the clinical data on 1088 patients with vitiligo.The relationship between possible inducements to the progression of vitiligo and lesion area was statistically analyzed in patients with the same clinical course of vitiligo. Paired t test was performed to compare the mean area index of involvement between patients with inducements and those without Results A significant difference was observed in the mean area index of involvement between patients with isomorphic response and those without (t = 6.770, P ＜ 0.01 ) as well as between patients negatively affected by psychiatric factors and those unaffected (t = 6.704, P ＜ 0.01 ), but not between patients with family history and those without (t = 1.499,P ＞ 0.05). Conclusion A rapid progression of vitiligo is more likely to be observed in patients negatively affected by psychiatric factors and patients with isomorphic response.