Induced pluripotent stem cell inductive system: status quo and future
10.3760/cma.j.issn.1673-4181.2010.06.013
- VernacularTitle:诱导多能干细胞诱导体系研究现状及进展
- Author:
Jingtao YANG
;
Qiang SHE
- Publication Type:Journal Article
- Keywords:
Somatic cells reprogramming;
Induced pluripotent stem cells;
iPS inductive system;
Transcription factor;
small molecules
- From:
International Journal of Biomedical Engineering
2010;33(6):372-375
- CountryChina
- Language:Chinese
-
Abstract:
Induced pluripotent stem(iPS)-cell technology is a great breakthrough in stem cell research field in recent years, it is not only injecting new vitality for the research of reprogramming of somatic cell, but also bringing a new dawn to the study of mechanism of disease and development of regenerative medicine. As key issues of iPS-cell technology, the study of iPS cell induction system has progressed in the composition of transcription factor, gene delivery, as well as induction efficiency. In this article, research advance of iPS cell induction system in recent years is reviewed and the prospect is discussed as well.
