Selection of feeding artery used for regional intra-arterial infusion in severe acute pancreatitis
10.3760/cma.j.issn.1007-8118.2011.01.006
- VernacularTitle:重症急性胰腺炎区域灌注治疗供药动脉的选择
- Author:
Mengtao ZHOU
;
Chang YU
;
Weizhong ZHOU
;
Wenhao HU
;
Qitong SONG
;
Zhengping YU
;
Zhengkeng XU
;
Qiyu ZHANG
- Publication Type:Journal Article
- Keywords:
Severe Acute Pancreatitis;
Regional Arterial Infusion;
Angiography;
Artery
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(1):17-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the ideal choice of feeding artery which is used for regional arterial infusion (RAI) in severe acute pancreatitis. Methods Forty-five patients with SAP were treated with RAI. The ideal feeding artery was that can supply entire pancreas according to arteriography and can maximize concentration of drug at pancreatic tissue. The pancreatic arteriography was considered as the final objective evidence for choice. Results (1)Gastroduodenal artery was chosen as feeding artery in forty-four cases, and superior mesenterlc artery was chosen in only one case because of vascular abnormity. (2)According to splenic arteriography, blood of splenic artery was supplied to spleen chiefly, and only partial tail of pancreas was applied by splenic artery. (3)According to celiac trunk arteriography, blood of celiac trunk could be supplied to entire pancreas, but a considerable proportion of the total blood was supplied to spleen through splenic artery and liver through hepatic artery proper.Therefore, the drug utilization index was lower. (4)According to gastroduodenal arteriography, blood of gastroduodenal artery could be supplied to entire pancrea, and almost all of the blood that contains drug flowed into pancreas. Therefore, the drug utilization index was higher. Conclusions Gastroduodenal artery is the ideal choice of artery which is used for regional intra-arterial infusion in sever acute pancreatitis. Pancreatic arteriography should be applied routinely when yever acute pancreatitis was treated with RAI.
