Evaluation of cerebrovascular reserve by xenon computed tomography in patients with ischemic stroke
10.3760/cma.j.issn.0578-1426.2011.01.010
- VernacularTitle:氙CT对缺血性脑血管病血管储备功能的研究
- Author:
Wenjie CAO
;
Qiang DONG
- Publication Type:Journal Article
- Keywords:
Cerebrovascular disorders;
Regional blood flow;
Xenon-enhanced CT
- From:
Chinese Journal of Internal Medicine
2011;50(1):32-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the cerebrovascular reserve(CVR) in patients of ischemic stroke with cerebrovascular stenosis by Xenon-enhanced CT. Methods Twenty subjects of ischemic stroke with cerebrovascular stenosis were recruited. All subjects were examined by Xenon-enhanced CT before and after acetazolamide (ACZ) challenge test to quantitatively measure the regional cerebral blood flow (rCBF) and CVR. Results We compared the rCBF in the corresponding region supplied with stenosed artery (divided manually) with that in the region of normal side. There was no significant difference in resting rCBF but in CVR [ipsilateral side vs. normal side ( 5.9 ± 24. 3 ) % vs ( 25.9 ± 32. 6 ) % , P ＜ 0. 05]. Conclusion Impaired CVR is an important character of the patients with cerebrovascular stenosis suffered from ischemic stroke.
