Cutaneous Plasmacytoma Associated with Multiple Myeloma.
- Author:
Sung Ku AHN
;
Seung Hun LEE
;
Dong Hwan SHIN
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Plasmacytoma;
Monoclonality;
Radiotherapy
- MeSH:
Biopsy;
Bone Marrow;
Endoplasmic Reticulum, Rough;
Humans;
Immunoglobulin G;
Melphalan;
Middle Aged;
Multiple Myeloma*;
Peroxidase;
Plasma Cells;
Plasmacytoma*;
Prednisolone;
Radiotherapy
- From:Korean Journal of Dermatology
1987;25(6):854-857
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 52-year-old man with multiple myeloma developed cutaneous nodules while being treated with melphalan and prednisolone. A biopsy specimen showed dermal infiltration by well differentiated plasma cells similar to those found on bone marrow biopsy. The use of peroxidase anti-peroxidase to demonstrate the monoclonality or polyclonality of the cytomplasmic immunoglohulins in the tumor cells revealed a positivity for IgG and 1 chain (ie, monotypic staining). Ultrastructurally, each plasmacytoma cell contained varyting amounts of rough endoplasmic reticulum and Golgi-apparatus. The cutnneous nodules completely disappeared after radiotherapy
