Standardized medication strategy for new diagnosed epilepsy

VernacularTitle:新诊断癫痫患者的规范化药物治疗
Author: Guoxing ZHU ; Xunyi WU ; Peimin YU ; Jinyang WANG ; Yue ZHANG ; Zhen HONG
Publication Type:Journal Article
Keywords: Epilepsy; Drug therapy; Clinical protocols
From: Chinese Journal of Neurology 2011;44(1):6-9
CountryChina
Language:Chinese
Abstract: Objective To formulate and detect the efficacy and safety of standardized medication strategy of epilepsy. Methods The normalized medication strategy was worked out in 278 new diagnosed patients, whose effect, retention rate and safety were evaluated after 24 months of treatment. Results Of all the 278 patients, 235 patients were taken mono-therapy while other 43 patients used therapeutic alliance.Most patients took CBZ or VPA as mono-therapy drugs. At the time after 24 months, almost 76. 3%(212/278) patients got seizure free, and the effectiveness was 22. 7% (63/278). The retention rate of those mono-therapy drugs were investigated respectively. CBZ presented 69. 8%, VPA presented 76. 2%,OXC was 68.0%, TPM was 69. 6%, LTG was 83. 3%, LEV presented 85.7%, and 100% for PHT.Conclusions All epileptic patients were well-controlled after taking standardized medication. The standardized medication strategy of epilepsy possesses valuable importance in clinical practice, which deserves further popularization.