Epidemiology and risk factors of invasive fungal infections in old patients for non-respiratory tract
10.3760/cma.j.issn.1673-4904.2011.03.002
- VernacularTitle:老年患者非呼吸道侵袭性真菌感染的流行病学及危险因素
- Author:
Wenli FENG
;
Zhiqin XI
;
Jing YANG
;
Yanqing WANG
;
Runmei ZHANG
;
Ying JI
;
Yuan WU
;
Xiaoqiang JIA
- Publication Type:Journal Article
- Keywords:
Aged;
Fungi;
Risk factors
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(3):4-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiology and relevant risk factors of invasive fungal infection (IFI) in hospital old patients for non-respiratory tract. Methods Seventy-eight patients of IFI in non-respiratory tract were enrolled in this investigation. The incidence and risk factors of IFI were analyzed by prospective case-control study. Results In 78 old patients, 84 strains were isolated from different parts, and the most was Candida spp 82 strains (97.62%,82/84), followed by Candida albicans 55 strains (67.07%,55/82), Candida glabrata 13 strains ( 15.85%, 13/82), Candida krusei 6 strains (7.32%, 6/82), Candida tropicalis 4 strains (4.88% ,4/82), Candida parapsilosis 3 strains (3.66% ,3/82), Candida lusitaniae 1 strain ( 1.22%, 1/82). Aspergillus 2 strains (2.38%,2/84). Multivariate Logistic regression analysis showed that age, pathogen detection time, underlaying disease,glucocorticoids, immunosuppressants were the risk factors for IFI in non-respiratory tract. Conclusions Candida albicans is the main pathogens of Candida infections in old patients. To efficiently control the risk factors should be emphasized in old patients, including early diagnosis and treatment underlying diseases, appropriate use drugs, right to shorten hospital stay.
