Relationship between preoperative biochemical indexes and effect of postoperative first 131I internal irradiation for differentiated thyroid carcinoma

VernacularTitle:术前生化指标与分化型甲状腺癌术后首次131I内照射疗效的关系
Author: Kun HU ; Shengrong SUN
Publication Type:Journal Article
Keywords: Thyroid neoplasms; Idoxuridine; Alkaline phosphatase; Thyrotropin
From: Chinese Journal of Postgraduates of Medicine 2011;34(2):19-21
CountryChina
Language:Chinese
Abstract: Objective To analyze the relationship between preoperative biochemical indexes and effect ofpostoperative first 131I internal irradiation for differentiated thyroid carcinoma. Methods One hundred and eighty patients of thyroid carcinoma within the first 131I internal irradiation postoperative. According to curative effect were divided into effective group (96 cases) and invalid group (84 cases) and their clinical data were retrospectively analyzed. Results The preoperative serum alkaline phosphatase (AKP) and thyroid-stimulating hormone (TSH) in effective group and invalid group were respectively (74.83 ± 19.77),(65.50 ± 11.84) U/L and (3.12 ±0.59), (2.57 ±0.56) mU/L. There were significant difference (t =3.77,6.39, P < 0.01) between two groups. Conclusion The levels of preoperative serum A KP and TSH are important factors to influence the effect of postoperative first 131I internal irradiation for differentiated thyroid carcinoma.