Apnea Associated with General Anesthesia in the Surgical Treatment of Retinopathy of Prematurity and its Risk Factors.
- Author:
Kyoung Bok KANG
1
;
Jong Mo SEO
;
Young Suk YU
;
Hee Soo KIM
;
Chong Sung KIM
;
Beyong Il KIM
;
Jung Hwan CHOI
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University.
- Publication Type:Original Article
- Keywords:
Postanesthetic apnea;
Retinopathy of Prematurity
- MeSH:
Anesthesia;
Anesthesia, General*;
Apnea*;
Birth Weight;
Bradycardia;
Bronchopulmonary Dysplasia;
Gestational Age;
Humans;
Infant, Newborn;
Logistic Models;
Respiration, Artificial;
Retinopathy of Prematurity*;
Retrospective Studies;
Risk Factors*;
ROC Curve
- From:Journal of the Korean Ophthalmological Society
2000;41(2):488-494
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We evaluated the relationship between preoperative risk factors[gestational age, birth weight, postconceptual age and weight at operation, duration of operation, duration of anesthesia, abnormalities in neurosonogram, bronchopulmonary dysplasia]and apnea with or without bradycardia, for which mechanical ventilation was necessary after general anesthesia in the surgical treatment of retinopathy of prematurity[ROP]. Thirty-eight patients [21%]developed apnea and thirteen patients[7%]had bradycardia out of 183 patients. Retrospective study was performed and risk factors were analyzed by logistic regression. Gestational age, birth weight, postconceptual age and weight at operation and bronchopulmonary dysplasia showed the positive correlation with postanesthetic apnea and bradycardia. Duration of operation showed the positive correlation with postanesthetic apnea but not with postanesthetic bradycardia. In logistic regression without confoundings, weight at operation and bronchopulmonary dysplasia were correlated with postanesthetic apnea. Receiver operating characteristic curve analysis revealed that patients with weight under 2, 600gm at operation suffered from apnea more frequently than those with weight over 2, 600gm. In conclusion, patients with weight under 2600gm or bronchopulmonary dysplasia are at greater risk for postanesthetic apnea and optimal pre-and postanesthetic management should be prepared for these patients.
