Effects of dexmedetomidine-propofol-fentanyl combined anesthesia on somatosensory and motor evoked potentials in patients undergoing cervical spine surgery
10.3760/cma.j.issn.0254-1416.2010.11.002
- VernacularTitle:右美托咪啶-异丙酚-芬太尼复合麻醉对颈椎手术病人体感诱发电位及运动诱发电位的影响
- Author:
Sheng LIN
;
Shuqin NI
;
Dongxiu SUN
;
Wei SHAO
;
Binghua SHEN
- Publication Type:Journal Article
- Keywords:
Medetomidine;
Propofol;
Fentanyl;
Evoked potentials,somatosensory;
Evoked potentials,motor
- From:
Chinese Journal of Anesthesiology
2010;30(11):1284-1286
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of dexmedetomidine-propofol-fentanyl combined anesthesia on somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) in patients undergoing cervical spine surgery. Methods Thirty-six patients undergoing cervical spine surgery were randomly divided into 2 groups (n = 18 each): propofol-fentanyl combined anesthesia group (group C) and dexmedetomidine-propofol-fentanyl combined anesthesia group (group D). Anesthesia was induced with TCI of propofol and iv injection of fentanyl.After the consciousness disappeared, a laryngeal mask airway was placed and the patients were ventilated. In group D, dexmedetomidine 0.5 μg/kg was injected over 10 min after the consciousness disappeared, followed by an infusion at a rate of 0.5 μg·kg-1 ·h-1 until the end of surgery. In group C, the equal volume of normal saline was administered instead of dexmedetomidine. SEPs (P15-N20) amplitudes and latency were measured and recorded before dexmedetomidine administration and at 10 min of dexmedetomidine infusion. The no-elicitation of MEPs was recorded. Results Compared with group C, there was no significant difference in P15-N20 amplitudes and latency in group D. The no-elicitation rate of MEPs in two groups was 0. Conclusion Dexmedetomidine-propofol-fentanyl combined anesthesia does not affect SEPs and MEPs in patients undergoing cervical spine surgery.
