Progress in treatment of acute lymphoblastic leukemia in adolescents
10.3760/cma.j.issn.1673-4408.2011.01.014
- VernacularTitle:青少年急性淋巴细胞白血病治疗进展
- Author:
Na ZHANG
- Publication Type:Journal Article
- Keywords:
Acute lymphoblastic leukemia;
Adolescents;
Children;
Adults
- From:
International Journal of Pediatrics
2011;38(1):38-40
- CountryChina
- Language:Chinese
-
Abstract:
The development of effective therapy for children with acute lymphoblastic leukemia (ALL) is one of the greatest successes of clinical oncology. However, cure rates for adults with ALL remain relatively low. Adolescents are the special population between children and adults. These patients group will be received protocol from either pediatric or adult oncologists depending on referral pattern. In recent years, researchers from abroad large cooperative groups show pediatric-based protocol has better outcome than adult-based protocol. In this article, the protocol of ALL in children and adults are compared . It seems the first and probably the most important reason is the dose intensity of the nonmyelosuppressive chemotherapeutic agents, especially asparaginase.
