Effect of Rhodiola Crenulate oral liquid on reproduction function in male rats
10.3760/cma.j.issn.1673-4246.2011.01.007
- VernacularTitle:红景天口服液对雄性大鼠生殖功能的影响
- Author:
Danyan CAO
;
Zhenzhong LIU
;
Gang SUI
;
Guanghua ZHU
;
Xiaojiang TANG
- Publication Type:Journal Article
- Keywords:
Rhodiola Crenulate oral liquid;
Mating test;
Testosterone level
- From:
International Journal of Traditional Chinese Medicine
2011;33(1):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the action of Rhodiola Crenulate(RC) oral liquid reproduction function for the male rats. Methods 100 SD rats were randomly divided into 5 groups with equal gender number respectively. The male rats were given RC oral liquid (0, 2.48 g/kg, 7.48 g/kg, 24.80 g/kg) and Nanbao (2.00 g/kg)by oral twice a day for 48 d, respectively. Then the male rat was put into the same box in which the female rat whit two-side ovarys were excised for 15 d, respectively. The intercoursing ability,testosterone levels, and the weight of immune organs of the male rats were examined. 40 four-week-old rats were divided into 5 groups. Except for blank control, all rats's testis were excised. The castrated rats were treated with RC oral liquid (2.48 g/kg, 24.8 g/kg)and Methyltestosterone (2.00 mg/kg). The blank control group and model control group were given the same dose NS by oral twice a day for 28 d, respectively. The weight of accessory sex organs in castrated rats was observed. Results The level of testosterone and the organ coefficients of thymus and spleen in RC oral liquid groups were higher than blank control (P<0.05 or P<0.01).The weight of accessory sex organs of castrated rats in RC oral liquid groups were heavier than model control (P<0.05). Conclusion RC oral liquid can improve the reproduction function in male rats.
