Assessment of treatment efficacy in radiofrequency ablation for renal tumors by contrast-enhanced ultrasonography
10.3760/cma.j.issn.1000-6702.2011.01.012
- VernacularTitle:超声造影检查在肾肿瘤射频消融术后疗效评估中的应用价值
- Author:
Weiwei ZHANG
;
Wentao KONG
;
Junlan QIU
;
Hongqian GUO
;
Xiaogong LI
;
Weidong GAN
;
Zhiming JIANG
;
Yi SHEN
;
Shiwei ZHANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Imge enhancement;
Kidney neoplasms;
Radiofrequency ablation;
Treatment outcome
- From:
Chinese Journal of Urology
2011;32(1):31-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the utility of contrast-enhanced ultrasonography (CEUS) in the assessment of treatment efficacy of radiofrequency ablation (RFA) in patients with renal tumors.Methods Forty-seven patients (40 renal cell carcinomas and 7 angiomyolipomas of kidney) with 49 renal tumors were treated with RFA. Tumors were ablated by laparoscopy-assisted (n= 30) and open surgical (n= 17) RFA. The CEUS and contrast-enhanced CT were performed 1 week after treatment to assess the necrotic area. Technical success was defined as elimination of areas that enhanced at imaging within the entire tumor. Results Forty-seven (95. 9%) of 49 tumors were successfully ablated. The mean length of the major axis at the maximal necrotic area was 4. 6 cm. Compared with the lesions before RFA, the necrotic areas were bigger in 45 patients, identical in 3 patients, and smaller in 1 patient. Six lesions showed a residual enhancement at the portion adjacent to the normal renal parenchyma on follow-up CEUS, while 2 were confirmed by CT scans. The sensitivity and specificity of CEUS for detection of residual tumors were 100. 0% and 91.8%, respectively. All patients survived in the follow-up period ranging from 4 to 21 months. Conclusion CEUS combined with CT could be useful for evaluating treatment efficacy of RFA for renal tumors.
