The neuropsychological and cortical metabolic changes in two patients with Benson's syndrome
10.3760/cma.j.issn.1006-7876.2011.03.004
- VernacularTitle:Benson综合征患者两例神经心理特征与皮质代谢异常
- Author:
Jing GAO
;
Jiaxiang GUO
;
Fang LI
;
Feng FENG
;
Zhaohui ZHU
;
Na NIU
;
Hui YOU
;
Liying CUI
;
Yupu GUO
- Publication Type:Journal Article
- Keywords:
Cerebral cortex;
Atrophy;
Dementia;
Neuropsychological tests
- From:
Chinese Journal of Neurology
2011;44(3):163-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective Standard neuropsychological assessment plus structural and functional imaging were used in accurate diagnosis of Benson's syndrome (posterior cortical atrophy).Method Serial neuropsychological screening and integrative assessments of visual spatial function, 3D structural MRIimaging and functional FDG-PET imaging were used in two cases of Benson' s syndrome.Results The clinical signs were agnosia, optic ataxia, apraxia, alexia, agraphia and prosopagnosia.MRI imaging revealed bilateral parietal and occipital lobe atrophy.FDG-PET imaging revealed low metabolism in the posterior cortex.The agraphia was constructive: the words were correct but written in the wrong location.Conclusion Standard neuropsychological assessments can recognize the disease nature.When combined with the structural and functional imaging, a correct diagnosis of Benson's syndrome can be made.
