Comparative study of ultrasound elastosonography with pathology on hepatic fibrosis in patients with chronic hepatitis B
10.3760/cma.j.issn.1004-4477.2011.02.013
- VernacularTitle:慢性乙型肝炎肝纤维化超声弹性成像与病理对照研究
- Author:
Shuzhen CONG
;
Shufang PEI
;
Lifeng ZHOU
;
Kehong GAN
;
Kang LI
;
Zhanwu FENG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Hepatitis B,chronic;
Liver cirrhosis
- From:
Chinese Journal of Ultrasonography
2011;20(2):134-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of ultrasound elastosonography in the diagnosis of liver fibrosis. Methods One hundred and twenty patients with chronic hepatitis B were examined by ultrasound elastosonography and given elasticity scores,the correlation coefficient between the elasticity scores and the histologic fibrosis stage was evaluated and its difference in the diagnosis of liver fibrosis was compared. Results The Spearman's correlation coefficient between the elasticity scores and the histologic fibrosis stage was 0. 875,which was highly significant ( P<0. 01). There was no significantly difference between elasticity scores and fibrosis staging in the diagnosis of liver fibrosis by Marginal Homogeneity (Z=- 1. 144, P = 0. 149). The sensitivity,specificity and accuracy of ultrasonic elastography for diagnosing liver fibrosis were 92. 5%, 85.0%, 90.0%, respectively. Conclusions Elastosonography is helpful for the diagnosis of liver fibrosis.