Prevention and treatment for chemotherapy-induced peripheral neuropathy: a review
10.3760/cma.j.issn.1673-422X.2011.02.009
- VernacularTitle:化疗药物所致周围神经病变的防治
- Author:
Zhengfeng ZHU
;
Xin LI
;
Mingzhi ZHANG
- Publication Type:Journal Article
- Keywords:
Drug therapy;
Peripheral nerves;
Drug toxicity;
Chemoprevention
- From:
Journal of International Oncology
2011;38(2):108-110
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy- induced peripheral neuropathy (CIPN) can be caused by many commonly used chemotherapeutic agents, such as taxanes, vinca alkaloids, platinum drugs, thalidomide,and also by newer agents such as bortezomib. Both animal experiments and clinical studies are being conducted to investigate strategies for preventing CIPN or ameliorating established CIPN without affecting the antitumor efficacy of chemotherapy. Treatments using calcium and magnesium infusions,glutathione,lipoid acid are being evaluated for their clinical application.
