Let-7 and its function in lung cancer
10.3760/cma.j.issn.1673-422X.2011.02.018
- VernacularTitle:let-7及其在肺癌中的作用
- Author:
Xihua LAI
;
Maosheng WANG
- Publication Type:Journal Article
- Keywords:
MircoRNAs;
Lung neoplasms;
Early diagnosis;
Therapeutic uses;
Let-7 microRNA
- From:
Journal of International Oncology
2011;38(2):136-138
- CountryChina
- Language:Chinese
-
Abstract:
Let-7 is found to be downregulated in lung cancer while many kinds of oncogenes expression always increase, and restoration of the let-7 to normal expression level inhibits lung cancer growth evidently.Thus, let-7 might serves as good targets or effective interference tools in exploration of anticancer therapeutics,and has a good prospect in applying it in the early diagnosis, prognosis and therapy in lung cancer.
