The prevalence of organ failure and its risk factors in patients with severe acute pancreatitis
10.3760/cma.j.issn.1671-0282.2011.02.011
- VernacularTitle:重症急性胰腺炎患者器官功能衰竭的患病率及其危险因素分析
- Author:
Xiaoyan LI
;
Xiaobo WANG
;
Xiufeng LIU
;
Shugui LI
- Publication Type:Journal Article
- Keywords:
Severe acute pancreatitis;
Organ failure;
Prevalence;
Risk factor;
Age;
Comorbidit;
APACHE Score;
Pancreatic necrosis;
Abdominal compartment syndrome
- From:
Chinese Journal of Emergency Medicine
2011;20(2):156-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the prevalence of organ failure and its risk factors in patients with severe acute pancreatitis(SAP). Method A retrospective analysis was conducted in 186 patients, who were hospitalized in the intensive care unit of Jinzhong First People's Hospital with SAP between March 2000and October 2009. SAP patients met the diagnostic criteria of SAP set by Surgery Society of Chinese Medical Association in 2006. The variables included age, gender, etiology of SAP, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CT Severity Index ( CTSI ), abdomen compartment syndrome (ACS) ,the number of organ failure and the number of death. The prevalence and mortality of organ failure were calculated. The above-mentioned variables were analyzed by unconditional multivariate logistic regression analysis to determine the independent risk factors for organ failure in SAP. Results Of 186 patients, 96had organ failure. In 96 patients with organ failure, 47 died. There was a significant association between the prevalence of organ failure and age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis, CTSI, ACS. An increase in age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis correlated with an increase in the number of organ failure. Age, the number of comorbidit, APACHE Ⅱ score,CECT pancreatic necrosis, CTSI and ACS went into the unconditional multivariate logistic regression equation. Conclusions Organ failure occurred in 51.6% of 186 patients with SAP. The mortality of SAP with organ failure is 49.0%. Age, the number of comorbidit, APACHE Ⅱ score, CECT pancreatic necrosis,CTSI and ACS are independent risk factors of organ failure.
