Effect of Helicobacter pylori infection on plasma lipid and high sensitive C reactive protein levels in patients with cerebral infarction
10.3760/cma.j.issn.1673-4904.2011.06.008
- VernacularTitle:脑梗死患者幽门螺杆菌感染对血脂和超敏C反应蛋白的影响
- Author:
Junhan ZHANG
;
Xiaoyan YANG
;
Hong LIU
;
Xuemei CHI
;
Jinbiao QIAO
;
Na YUAN
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Helicobacter pylori;
C-reactive protein;
Plasma lipid
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(6):18-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Helicobacter pylori (Hp) infection on plasma lpid and high sensitive C reactive protein (hs-CRP) levels in patients with cerebral infarction, and explore the pathogenesy. Methods Seventy-nine cerebral infarction patients without nearly inflammatory reaction disease were recruited. Hp was detected by breath test,the patients were divided into infection-negative group (15 cases), light infection group (29 cases) and severe infection group(35 cases) according to the results,the last two groups were as infection-positive group. The plasma lipid and hs-CRP levels were exanined.Results Compared with infection-negative group,the total cholesterol,low density lipoprotein,hs-CRP levels increased obviously in infecton-positive group (P ＜ 0.05). The level of hs-CRP in severe infection group was higher than that in light infection group [(10.21 ±4.98) mg/L vs. (5.81 ±4.21) mg/L](P=0.001 ). Conclusions Hp infection may increase vascular inflammatory reaction through lipid metabolic disturbance. The cerebral infarction with higher Hp infection, and with the degree of infection increased, the risk is also increased accordingly.
