Effect of HbA1c meeting the standard or not on microalbuminuria,blood lipids and liver enzymes in patients with type 2 diabetes
10.3760/cma.j.issn.1008-1372.2011.02.007
- VernacularTitle:2型糖尿病患者HbA1c是否达标对尿蛋白、血脂及肝酶的影响
- Author:
Keying ZHANG
;
Peng CAO
;
Jian DU
;
Yinan YU
;
Yun LI
;
Hongfei LUO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2/ME;
Hemoglobin A,glycosylated/ME;
Albumins/ME;
Lipid metabolism;
Liver/EN
- From:
Journal of Chinese Physician
2011;13(2):167-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of HbA1c meeting the standard or not on microalbuminuria,blood lipids and liver enzymes in patients with type 2 diabetes.Methods A retrospective analysis was performed on 457 subjects who had type 2 diabetes.They were divided into substandard group and standard group according to HbA1c result.The general information and relevant laboratory indicators of patients were.collected and compared between two groups.Results The microalbuminuria,serum triglyceride and liver enzymes (glutamyl transpeptidase,alkaline phosphatase,aspertate aminotransferase) were significantly different between two groups [ (189.8 ± 235.3) mg/dl vs (38.9 ± 85.5) mg/dl,(2.64 ± 2.99) mmol/L vs (2.02 ± 1.50)mmol/L,(41.7 ±52.9)U/L vs (29.7 ±24.9)U/L,(83.6 ±28.6) U/L vs (74.3 ±25.8)U/L,(26.7 ±19.1)U/L vs (22.0 ±10.5) U/L,P ＜0.05].HbA1c level was positively correlated with microalbuminuria,glutamyl transpeptidase and alkaline phosphatase (r =0.209,0.115,0.11,P ＜0.01).The microalbuminuria was an independent risk factor of affecting HbA1c to reach the standard (OR = 1.009,P ＜0.05).Conclusions HbA1c meeting the standard or not can influence many factors except blood glucose.
