Advances in research of let-7 in cancer
10.3760/cma.j.issn.1673-422X.2011.02.003
- VernacularTitle:let-7在肿瘤中的研究进展
- Author:
Xiuming ZHU
;
Lingjiao WU
;
Fusheng WU
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Let-7
- From:
Journal of International Oncology
2011;38(2):89-92
- CountryChina
- Language:Chinese
-
Abstract:
Let-7 is one of the most widely studied in miRNAs at present. let-7 can inhibit cell proliferation, promote cell differentiation and apoptosis, etc. Reduced expression of let-7 in different human tumor tissues or cells is accompanied by the changes of its target genes expression, which suggests that let-7 is closely linked to cancer.
