The expression of Fas ligand in esophageal carcinoma and its clinic significance.

VernacularTitle:食管癌的Fas配体表达及意义
Author: Wenwu GAO ; Zhifei XU
Publication Type:Journal Article
From: Chinese Journal of Thoracic and Cardiovascular Surgery 2001;17(2):87-89
CountryChina
Language:Chinese
Abstract: Objective: To determine the expression of Fas ligand (FasL) in the patients with esophageal carcinoma and its clinic significance. Methods: The expression of FasL was measured by immunohistochemical technique in 30 patients with esophageal cancer. The numbers of tumor infiltrationg (TIL) were accounted by immunohistochemically stained CD45. Results: 76.6% of specimen expressed FasL. The difference of FasL expression was significant between each TNM stage. There was a negative correlation between the number of TIL and the expression of FasL. Conclusion: The expression of FasL in esophageal carcinoma may correlate with its invasion and metastasis.