Preliminary study of P3b potential in rats
- VernacularTitle:大鼠P3b波实验研究
- Author:
Qian YU
;
Xiaohong LI
;
Zongyao WU
- Publication Type:Journal Article
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2001;23(2):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the characteristics and mechanism of P3b potentials in rats and establish the animal model of P3b.Methods P3b potentials and cell electric discharge in hippocampal CA1 region were recorded simultaneously inside cranio, septal and hippocampal CA1 region in rats.After septal lesions,the changes of P3b and cell electric discharge in hippocampal CA1 region were observed.Results P3b in hippocampal CA1 region was correlated well with its cell electric discharge. Following septal lesions,P3b and cell electric discharge decreased gradually and disapeared eventually. Conclusion Cell electric discharge in hippocampal CA1 region might be an important source of P3b.Normal structure and function of septal region were necessary to P3b's generation in hippocampal CA1 region. Additionally these suggested that cell electric discharge to target stimulation was important to P3b's generation.
