Evaluation of the dinical curative effect of using 153Sm-EDTMP in painful bone metastasis of malignant tumor
- VernacularTitle:153Sm-乙二胺四甲基撑膦酸治疗恶性肿瘤骨转移疼痛
- Author:
Xiaojuan ZHANG
;
Jianhua JIN
;
Jianzhong LIU
;
Sijin LI
;
Xianfeng LI
;
Chengang ZHANG
;
Rui GUO
;
Yanli NING
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
153Sm-EDTMP;
Pain
- From:
Cancer Research and Clinic
2008;20(3):182-184
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical curative effect of using 153Sm-EDTMP in painful bone metastasis of malignant tumor. Methods Eighty patients with bone metastasis of malignant rumor underwent radionuclide bone palliation therapy were analysed.The treatment efficacy was evaluated by visual analogue scale (VAS) and Kamofsky performance scale.Results 68.75% of patients had a positive response.A better analgesic effect was found in cases of lung,prostate and breast carcinoma metastasm compared to metastasis from other malignant lesions.Improvement of performance in Karnofsky scale was found in cases of midrange and heavy range patients.Conclusion The analgesic effects of 153Sm-EDTMP is obvious in painful bone metastasis of malignant tumor.Improvement of life quality is significant in cases of midrange and heavy range patients.The therapeusis is a beneficial supplement of radiotherapy and odynolysis therapy.
