The impact of VEGF-C on lymph-node metastasis of breast cancer
- VernacularTitle:淋巴管生成因子对乳腺癌淋巴结转移的影响
- Author:
Jun Lü
;
Ying ZHAO
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Vascular endothelial growth factor-C;
Immunohistochemistry;
Neoplasms metastasis
- From:
Cancer Research and Clinic
2007;19(z1):60-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the VEGF-C on lymph node metastasis of b-reast cancer.Methods A group of immune PV9000 law on human breast infiltrating ductal breast cancer and fibroids,breast disease organizations paraffin sections were detected on the expression of VEGF-C status.Results 20 patients with breast fibroids and breast disease were negative VEGF-C,80 cases of breast cancer VEGF-C positive rate was 72.5%(58/80);VEGF-C exists primarily on the cancer cells and normal breast fibroids and in the cytoplasm of breast disease is not the expression of VEGF-C.Conclusion Breast cancer cells in the VEGF-C,the expression of close ties with lymph node metastasis.Detection of VEGF-C expression in human breast cancer may predict lymph node metastasis,and therapeutic value.
