Clinical study of celiac ganglion block guided by endoscopic ultrasonography on celiac cancer pain
- VernacularTitle:超声内镜引导下腹腔神经节阻滞术治疗癌性疼痛的临床研究
- Author:
Luowei WANG
;
Zhendong JIN
;
Zhaoshen LI
;
Duowu ZOU
;
Xianbao ZHAN
;
Jie CHEN
;
Renpei WU
- Publication Type:Journal Article
- Keywords:
Abdominal pain;
Abdominal neoplasms;
Endosonography;
Celiac plexus neurolysis
- From:
Chinese Journal of Digestion
2008;28(5):297-300
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and salty of endoscopic ultrasonography-guided celiac plexus neurolysis (EUS-CPN) in the treatment of pain due to pancreatic cancer and celiac metastatic carcinoma.Methods Thirty-three patients with celiac carcinoma were selected for EUS-CPN. Among whom 15 pateints were received chemotherapy before procedure . Using endoscopic ultrasounography,transgastric injection of the celiac plexus with bupivacaine and 98% dehydrated absolute alcohol was accomplished.The abdominal pain was evaluated by the numeric pain intensity scale before and at 24,48,72 hours and one week after the precedure.The successful rate of precedure,the complication and the relief of the pain were observed. Results All procedures were performed successfully . No serious complications such as pancreatitis by trauma,pancreatic fistula,bleeding and celiac infection was found.Compared with baseline,pain was significantly relieved at 12,24,72 hours and 1 week after EUS-CPN (100%,98%,90% and 88%,respectively).The pain remission at 24,48,72 hours and one week in patients who received chemotherapy before procedure were 100%,100%,980% and 98%,respectively,while in those who had not treated chemically were 100%,98%,95% and 90%,respectively.The complete%relief of pain in chemotherapy group was significantly higher than that in nonchemotherapy group (75 % vs 56 %,P%0.05).Conclusions EUS CPN is a safe and effective method for relieving pain with low complications.It can raise the quality life of the patients and chemical therapy may be helpful in pain control.
