Predicting role of molecular gene marker in targeted therapy of non-small-cell lung cancer
- VernacularTitle:分子基因指标对非小细胞肺癌靶向治疗的预测作用
- Author:
Baohui HAN
;
Zhiqiang GAO
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Targeted therapy;
Treatment outcome;
Forecasting
- From:
Cancer Research and Clinic
2008;20(5):295-298
- CountryChina
- Language:Chinese
-
Abstract:
After many targeted drugs have entered into the treatment guideline or all stage clinical trial of non-small-cell lung cancer (NSCLC), many researchers undertake deep investigation on the role of molecular gene marker in targeted therapy of NSCLC. It is a good outset that mutation detection of epidermal growth factor receptor (EGFR) gene direct the selection of EFGR tyrosine kinase inhibitors (EGFR-TKI). To choose individualized therapy regimens according to molecular gene marker will be the important research direction, but also be the critical measure to improve the management level of NSCLC and prolong patient"s survival. Accompanied with deep investigation of targeted therapy, there will be more molecular gene markers to direct the formulation of individualized therapy regimens.
