Factors analysis on circadian rhythm of interdialytic blood pressure in maintenance hemodialysis patients
- VernacularTitle:维持性血液透析患者透析间期血压节律影响因素的分析
- Author:
Yalin LI
;
Jianying NIU
;
Lin TAO
;
Peng WANG
;
Peng LI
;
Weifeng FAN
;
Lihong LUO
;
Qi ZHANG
;
Yong GU
- Publication Type:Journal Article
- Keywords:
Renal dialysis;
Circadian rhythm;
Hypertension;
Ambulatory blood pressure monitoring;
Parathyroid hormone
- From:
Chinese Journal of Nephrology
2008;24(4):235-239
- CountryChina
- Language:Chinese
-
Abstract:
Objective To describe the circadian profiles of interdialytic blood pressure in maintenance hemodialysis patients and to investigate its related factors. Methods Ambulatory blood pressure monitoring (ABPM)was conducted in forty-four patients on regular hemodialysis during interdialytic days.Three groups were identified with their ambulatory blood pressure:non-hypertension group,controlled hypertension group and uncontrolled hypeaension group.Hemoglobin,creatinine,Kt/V,serum total calcium,serum phosphate,immunoreactive parathyroid hormone(iPTH),interdialytic weight gain and Morisky self-report scale etc.were assessed. Results (1)No significant difference was found in ABPM index ranged from decline in nocturnal systolic and diastolic blood pressure,AASI to dipper percentage in three groups.Nevertheless,24-h average pulse pressure in uncontrolled hypertension group was higher than the other groups[(80.06+13.41)vs(53.00±7.73),(57.85±21.97)mm Hg,all P＜0.01].(2)All the three groups showed the blood pressure profile of double-peak and trough.In the uncontrolled hypertension group,however,the nocturnal blood pressure decrease was not notable.(3)Nocturnal systolic blood pressure decline Was negatively correlated to iPTH(r=-0.039,P＜0.05).(4)In ten dippers out of all 44 patients,AASI was negatively correlated with nocturnal diastolic blood pressure decline (r=-0.748,P＜0.05). Conclusion Nocturnal blood pressure decline is correlated to iPTH and arterial selerosis.
