The effect of NB-UVB on stable vitiligo accompanied with autologous epidermis grafting
- VernacularTitle:窄谱中波紫外线预照射对自体表皮移植治疗稳定期白癜风的疗效影响
- Author:
Huiying CHEN
;
Qimin FAN
;
Dongdi ZHENG
;
Aie XU
- Publication Type:Journal Article
- Keywords:
Vitiligo;
Ultraviolet,Narrow-band;
Grafting,Epidermal
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2008;30(4):257-259
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effect of narrow-band ultraviolet(NB-UVB)on stable vitiligo with autologous epidermis grafting.Methods A total of 82 patients with stable vitiligo were recruited and randomly divided into a control group and a treatment group.The patients in the treatment group were pretreated with NB-UVB before autologous epidermis grafting,while those in the control group were not.The pretreatment with NB-UVB was implemented twice a week for at least 4 weeks before the autologous epidermis grafting. A 3-month follow-up observation was conducted with regard to the effectiveness. Results Pretreatment with NB-UVB could significantly increase the survival rate of skin grafts and rate of repigment of leukoplakia,when compared with autologous epidermises transplantation alone.The rate of complete repigment raised significantly(P＜0.05),and so did the curative effect for vulgaris generalized vitiligo(P＜0.029).It was found that the curative effect on vitiligo was closely related to the frequency of NB-UVB radiation,location of leukoplakia,color of skin,and the time of repigment appearance. ConclusiOn Pretreatment with NB-UVB can significantly improve curative effect of autologous epidermis grafting on vitiligo.
