Value of integrated PET-CT with 18F-FDG in the diagnosis of non-small-cell lung cancer
- VernacularTitle:18F-FDG PET-CT显像诊断非小细胞肺癌的价值
- Author:
Yanji PAN
;
Guangyu WEI
;
Dejun LIU
;
Fengwen YU
;
Yanlin FENG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Tomography,emission-computed;
18F-FDG
- From:
Cancer Research and Clinic
2008;20(5):319-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of integrated PET-CT with 18F-FDG in the diagnosis of non-small cell lung cancer.Methods 91 patients with non-small-cell lung cancer(NSCLC)and 10patients with benign disease underwent integrated PET-CT from February 2004 to May 2005.Other diagnostic procedures were analysed. Results 91 patients with lung cancer were found by positive SUV and pathologically confirmed.Of the 10 patients with benign disease.positive SUV were found in 3 cases.2 cases with tuberculosis and 1 case with inflammatory pseudotumor were confirmed.Negative SUV were found in 7cases.1 case was incorrectly diagnosed by integrated PET-CT.The sensitivity,specificity and accuracy of integrated PET-CT in the diagnosis of NSCLC were 100%,90%,99%,respectively.Forty-eight of 91patients with lung cancer underwent operation.There were 30 cases with and 18 cases without mediastinal nodal metastases.There were two false negative cases and one false positive case.The sensitivity,specificity and accuracy of integrated PET-CT in the diagnosis mediastinal nodal metastases were 93.3%,94.4%,93.8%.respectively.Metastases were identified in 33 cases.Conclusion Functional metabolism and anatomy imaging are fused in integrated PET-CT.The primary site and metastases lesion are correctly diagnosed by integrated PET-CT.The accuracy of integrated PET-CT in the diagnosis of NSCLC is over 90%.
