Understanding the pathogenesis of various type in exudative AMD, using the rational therapy
- VernacularTitle:正确理解新生血管性疾病的发病机制,合理行使抗新生血管药物治疗
- Author:
Xiaoxin LI
- Publication Type:Journal Article
- Keywords:
Choroidal neovascularization/therapy;
Retinal neovascularization/therapy;
Antibodies,monoclonal/therapeutic use;
Photochemotherapy/methods;
Laser coagulation/methods
- From:
Chinese Journal of Ocular Fundus Diseases
2008;24(3):157-159
- CountryChina
- Language:Chinese
-
Abstract:
Up-regulation of vascular endothelial growth factor(VEGF)is demonstrated to be a key role in formation process of intraocular neovascularization.Anti-VEGF treatment is the breakthrough of intraocular neovascular diseases therapy.Intravitreal injection of anti-neovascularization drug looks to be an effective method on ocular neovascular diseases which with the advantages of good biocompatibility,low prices and longer intravitreal half-time etc.However,at present,it lack of multi-center study;the long-term efficacy and the systematic safety needs the further clinicsl verification.Various types of CNV showed the different therapeutic reactions to either PDT or Anti-VEGF agent,the treatment methods for exudative AMD include laser,PDT,and drug like Triamcinolone Acetonide,several anti-VEGF preparations.Therefore.understanding the pathogenesis of neovascular AMD and choosing a reasonable therapeutic methods are necessary.We should try to explore a safe,effective,economic,new approach.
