Polymorphism of Black Snake Venom RNase.I - Two distinct kinetical forms
- Author:
Nguyen Van Thiet
- Publication Type:Journal Article
- Keywords:
ribonuclease* Black Snake Venom
- MeSH:
Snake Venoms;
Ribonucleases;
Polymorphism, Genetic
- From:Pharmaceutical Journal
2003;0(6):167-170
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
In the study, using the kinetic method for the examination of the dependence between the specific activity of the enzyme and the concentration of the enzyme itself in the combined reaction, the researchers have proved that the Ribonuclease (R.Nase) molecule of the black cobra (Naja naja) venom exits at least in two interconvertible forms with the difference in specific activity of almost one grade. These two forms are probably the different oligomers or configurations, temporarily named as the kinetic forms of R.Nase found in the black cobra venom.
