Investigation on clinical features and prognostic factors in patients with localized primary small bowel stromal tumors
10.3760/cma.j.issn.0254-1432.2010.05.001
- VernacularTitle:原发局限性小肠间质瘤患者的临床特征及预后分析
- Author:
Rong FAN
;
Jie ZHONG
;
Zhengting WANG
;
Lifen YU
;
Yu WANG
;
Yonghua TANG
;
Yanbo ZHU
;
Weiguo HU
- Publication Type:Journal Article
- Keywords:
Gastrointestinal stromal tumors;
Intestine,small;
Prognosis
- From:
Chinese Journal of Digestion
2010;30(5):289-292
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively investigate the clinical features of localized primary small bowel stromal tumors (SBSTs) and the impacting factors for prognosis.Methods The clinical and pathological data of 89 consecutive SBSTs patients,with pathologically confirmed,who underwent complete resection in Ruijin hospital between January 2003 and September 2007 were collected and analyzed.All patients were followed up for assessment of tumor recurrence and metastasis.The impacts of clinical and pathologic factors on rate of disease free survival (DFS) of the patients was evaluated.Results In total of 89 follow-up patients,15 patients were diagnosed with tumor recurrence and 9 of them died.The tumor size,mitotic index and pathological risk stratification were statistically related with DFS (P=0.000,P=0.006,P=0.000,respectively) by using Kaplan-Meier univaritate analysis.Tumor size and mitotic index were proved to be independent prognostic factors for tumor recurrence by multivariate analysis COX regression model.Conclusions Tumor size and mitotic index are related with tumor recurrence,and can be regarded as independent predictive factors of tumor recurrence.
