Neoadjuvant therapy for rectal cancer
10.3760/cma.j.issn.1006-9801.2010.07.003
- VernacularTitle:直肠癌的新辅助治疗
- Author:
Huachong MA
;
Zhenjun WANG
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Neoadjuvant therapy;
Radiotherapy;
Chemotherapy;
Biological therapy
- From:
Cancer Research and Clinic
2010;22(7):440-442
- CountryChina
- Language:Chinese
-
Abstract:
The neoadjuvant therapy for rectal cancer included neoadjuvant radiotherapy, neoadjuvant chemotherapy, neoadjuvant chemoradiotherapy and neoadjuvant molecular targeted therapy. Recent reports on neoadjuvant therapy clearly showed a downstaging and downgrading effect on the primary rectal cancer. The rates of R0 resection and sphincter preservation were improved and local recurrence was decreased, but the long term survival was not improved. The results of using new chemotherapeutics and molecular targeted drugs in neoadjuvant therapy for rectal cancer were expected.
