Advancement of cetuximab combined with chemotherapy in the treatment of liver metastases from colorectal cancer
10.3760/cma.j.issn.1006-9801.2010.07.026
- VernacularTitle:西妥昔单抗治疗结直肠癌肝转移研究进展
- Author:
Xiaobo LIANG
;
Shenghuai HOU
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Liver neoplasms;
Neoplasm metastasis;
Cetuximab;
Chemotherapy,adjuvant
- From:
Cancer Research and Clinic
2010;22(7):501-504
- CountryChina
- Language:Chinese
-
Abstract:
High incidence of liver metastases from colorectal cancer was found. To the patients with liver metastases from colorectal cancer, regardless of whether the liver metastases could be resected or not, hepatectomy after neoadjuvant chemotherapy was recommended. The combination of cetuximab and chemotherapy based on irinotecan and oxaliplatin as the second-line and first-line for the liver metastases from colorectal cancer could get higher response and longer survival, and more patients got the chance of hepatectomy. However, cetuximab was only good for the colorectal cancer patients with wild-type k-ras.
