Meta-analysis of fish oil in the treatment of IgA nephropathy
10.3760/cma.j.issn.1001-7097.2010.06.007
- VernacularTitle:鱼油治疗IgA肾病的Meta分析
- Author:
Kai SONG
;
San JIANG
;
Yongbing SHI
;
Huaying SHEN
;
Xiaosong SHI
;
Donghua JIN
- Publication Type:Journal Article
- Keywords:
fish oils;
Glomerulonephitis,IgA;
Meta-analysis;
Randomized controlled trials
- From:
Chinese Journal of Nephrology
2010;26(6):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the efficacy of fish oil in the treatment of IgA nephropathy using the method of Meta-analysis. Methods Randomized controlled trials of fish oil in the treatment of IgA nephropathy were searched in the database of Cochrane library,PubMed, EMBASE and CNKI. Data extracted from the literatures were analyzed with Revman software (version 5.0). Results In comparison with the controlled group, proteinuria in the fish oil group was significantly decreased [SMD=-0.27, 95%CI (-0.52 to -0.03), P=0.03], while the renal function deteriorated [SMD=0.30,95%CI(0.05 to 0.55), P=0.02]. Conclusion Fish oil can decrease the proteinuria of IgA nephropathy, but can not prevent renal function from deterioration.