Research advance and clinical application of ELISpot assay
10.3760/cma.j.issn.1009-9158.2010.08.001
- VernacularTitle:ELISpot技术的研究进展及临床应用
- Author:
Jianqing XU
- Publication Type:Journal Article
- Keywords:
Enzyme-linked immunospot;
Epitope screening;
T cell affinity;
Diagnosis;
Differentiating diagnosis
- From:
Chinese Journal of Laboratory Medicine
2010;33(8):709-711
- CountryChina
- Language:Chinese
-
Abstract:
ELISpot assay has been widely used in basic and clinical research with its unique advantages. ELISpot is highly efficient in epitope screening, quantification of the epitope specific T cells, determining the TCR affinity and evaluating vaccine efficacy. In addition, ELISpot has been increasingly employed in diagnosis, differentiating diagnosis, evaluating patients' immune state, treatment efficacy, and evaluation of the prognosis. Overall, with the further improvement of this assay, ELISpot will play a critical role in the development of human health.
