High-frequency transcranial magnetic stimulation for alleviating post-stroke depression

VernacularTitle:高频重复经颅磁刺激辅助治疗脑卒中后抑郁的临床疗效观察
Author: Jin LIU ; Xiao LI
Publication Type:Journal Article
Keywords: Repetitive transcranial magnetic stimulation; Post-stroke depression; Hamilton depression rating scale
From: Chinese Journal of Physical Medicine and Rehabilitation 2010;32(7):513-515
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on post-stroke depression (PSD). Methods Sixty PSD patients were randomly divided into an rTMS group and a control group, each of 30 patients. In addition to conventional treatment, rTMS group members were given high-frequency rTMS treatment for 10 d while the control group were given sham stimulation. In order to test the efficacy, the two groups were compared using the Hamilton depression rating scale (HAMD) before and after 10 and 30 days treatment. Results After 10 days of treatment the rTMS group had significantly lower HAMD scores than before treatment, and average HAMD scores differed significantly between the rTMS group and the controls, with the former performing significantly better. There was no obvious difference in HAMD scores after 30 days of treatment between the two groups. Conclusions High-frequency rTMS is a safe and effective treatment for PSD.