Association Between Psoriasis and HLA - B27 Antigen.
- Author:
Hwan Pyo JEON
;
Jai Il YOUN
;
Yoo Shin LEE
;
Myoung Hee PARK
- Publication Type:Original Article
- Keywords:
HLA-B27;
Psoriasis;
Psoriatic arthritis
- MeSH:
Arthritis;
Arthritis, Psoriatic;
HLA-B27 Antigen;
Humans;
Psoriasis*;
Spondylitis
- From:Korean Journal of Dermatology
1990;28(2):159-164
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The frequency of HLA-B27 antigen in 24 patients with psoriasis vulgaris and 11 patients with psoriatic arthritis were examined using the standard micro-lympho- cytotoxicity technique. There was a high frequency of HLA-B27 in psoriatic spondylitis with or without peripheral arthritis (83.3%) compared to controls (4.7%) and the relative risk of HLA-B27 for developing psoriatic spondylitis was 82.5% which indicates a strong association between HLA-B27 and psoriatic spondylitis in Korean populations. However, there was no stastical significance observed in the groups of patients with peripheral arthritis alone or psoriasis vulgaris in regard to the frequency of HLA-B27.
