Clinical research on prediction marker of efficacy in advanced non-small cell lung cancer
10.3760/cma.j.issn.1006-9801.2010.09.002
- VernacularTitle:晚期非小细胞肺癌靶向治疗疗效预测标志物临床研究进展
- Author:
Caicun ZHOU
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Target therapy;
Biological marker
- From:
Cancer Research and Clinic
2010;22(9):581-584
- CountryChina
- Language:Chinese
-
Abstract:
Individualized therapy is the current trend of treatment in advanced non-small cell lung cancer, the key of individualized therapy is to administrer different treatment options through different biological markers or clinical markers. Currently, biological markers include EGFR protein expression, EGFR mutations, EGFR gene copy, k-ras mutation, EML4-ALK gene fusion, C-MET gene. Clinical markers include rash, pathological types, etc. This article will give a review about those biomarkers.