Efficacy of esomerphrazole in treatment of patients with gastroesophageal reflux disease between han and Inner Mongolia populations

VernacularTitle:埃索美拉唑在内蒙古地区不同民族间胃食管反流病治疗中的应用
Author: Rina SUO ; Haijing JI ; Sumin LI ; Chengliang YANG ; Cuiqin FU
Publication Type:Journal Article
Keywords: Gastroesophageal reflux; Ethnic groups; Therapy
From: Chinese Journal of Digestion 2009;29(7):476-478
CountryChina
Language:Chinese
Abstract: Objective To assess the therapeutic effect of esomerphrazole in treating patients with gastroesophageal reflux disease (GRED) between Han and Inner Mongolia populations.Methods Those who underwent endoscopic examination and had reflux disease questionnaire (RDQ) >12 from March 2006 to March 2008 were selected. The patients were divided into Han group and Inner Mongolia group with 120 each. All patients were received esomerphrazole 20 mg daily for 6 weeks. The patients were evaluated by RDQ questionnaire at 2nd, 4th and 6th week, and were reexamined by gastroscopy at 6th week. Results After two weeks, effective rate of 50% was achieved in both groups, but it was higher in Han group than in Inner Mongolia group at 4th and 6th week. After 6 weeks, the curative rate of RE was higher in Han group than in Inner Mongolia group. Conclusion The different nations ancl habits result in the different efficacy of esomerphrazole, which may be improved by prolonging time of medication and changing habits.