The value of gastrointestinal endoscopy in diagnosis of patients with typical heartburn

VernacularTitle:胃镜检查对有典型烧心症状患者的诊断价值
Author: Sui PENG ; Yinglian XIAO ; Lishou XIONG ; Minhu CHEN ; Min REN
Publication Type:Journal Article
Keywords: Gastroesophageal reflux; Heartburn; Endoscopy
From: Chinese Journal of Digestion 2010;30(9):581-584
CountryChina
Language:Chinese
Abstract: Objective To evaluate the value of endoscopic profile in an adult population with typical heartburn. Methods Clinical and endoscopic data were collected from 5042 consecutive outpatients who underwent routine upper endoscopy without any alarm features between March 2006 and Feb. 2007. Results Three hundred and thirteen (6.2%) patients were diagnosed as having typical heartburn. Of these, erosive esophagitis (EE) was found in 99 (31.6%) patients, Barrett's esophagus (BE) in 10 (3. 2%) patients, peptic ulcer disease (PUD) in 21 (6. 7%) patients and carcinoma in three (0.9 %) patients (1 with esophageal carcinoma and 2 with gastric adenocarcinoma).Multivariate analysis revealed that age＞50, male, overweight and alcohol use were independent risk factors for positive endoscopy findings (P＜0.05) and EE (P＜0.05) in heartburn patients. Male and Helicobacter pylori infection were independent risk factors for PUD (P＜ 0.05). Conclusions In China, patients with typical heartburn but without alarm features, early endoscopic examination may be helpful in avoiding missing diagnosis of tumor.