Endoscopic retrograde cholangiopancreatography by using carbon dioxide for malignant biliary obstruction
10.3760/cma.j.issn.1007-5232.2010.10.002
- VernacularTitle:二氧化碳气体造影在恶性肝门部胆道梗阻内镜诊治中的应用价值
- Author:
Wei LI
;
Ming JI
;
Yongjun WANG
;
Peng LI
;
Shutian ZHANG
- Publication Type:Journal Article
- Keywords:
Bile duct obstrction;
Cholangiography;
Endoscopy;
Drainage;
Carbon dioxide
- From:
Chinese Journal of Digestive Endoscopy
2010;27(10):509-512
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the safety and efficacy of endoscopic retrograde cholangiopancreatography(ERCP)by using carbon dioxide for malignant biliary obstruction.Methods A total of 60 patients with malignant biliary obstruction, hospitalized from September 2008 to February 2010, were randomly divided into 3 groups to receive ERCP by using carbon dioxide, contrast agent or magnetic resonance cholangiopancreatography(MRCP)without any agent.The safety and efficacy of 3 contrast methods were compared.Results Successful stent or drainage tube insertion was achieved in all patients.Carbon dioxide was superior to contrast agent in terms of lowering postoperative infection rate(P < 0.05), and it was also superior to MRCP for more effective drainage(P < 0.05).There was no significant difference in occurrence of postoperative pancreatitis and hyperamylasemia between 3 groups.Conclusion Using carbon dioxide during ERCP, safe and effective, is superior to use of contrast agent in less leukocyte increase, and to MRCP in more adequate drainage in patients with malignant biliary obstruction.Furthermore, there is no more risk of pancreatitis and hyperamylasemia.