Feasibility of endoscopic resection-closure for non-intraluminal gastric stromal tumors originating from the muscularis propria layer
10.3760/cma.j.issn.1007-5232.2010.10.006
- VernacularTitle:源于固有肌层的胃间质瘤行内镜下切除闭合术的可行性研究
- Author:
Linhong NING
;
Lei WANG
;
Chaoqiang FAN
;
Wei REN
;
Xia ZHANG
;
Hong GUO
;
Xianlong LIN
;
Yihui LI
;
Xiaoyan ZHAO
- Publication Type:Journal Article
- Keywords:
Gastrointestinal stromal tumors;
Gastrointestinal endoscopes;
Non-intracavitary submucosal tumors;
Endoscopic resection-sutura
- From:
Chinese Journal of Digestive Endoscopy
2010;27(10):526-528
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility of endoscopic resection and closure for non-intraluminal gastric stromal tumors originating from the muscularis propria layer.Methods Included in the study were 46 patients with gastric submucosal lesions originating from the muscularis propria layer, detected by gastroscopy and endoscopic ultrasonography.The lesions were removed by endoscopic resection and closure, which were further diagnosed as stromal tumor by means of pathologic and immunohistochemical examinations.The patients were followed up with endoscopy for evaluation of therapeutic effect and complications.Results All lesions were successfully removed, with serosa layer remained in 2 cases and full layer resection in other 44, which were all closed by endoscopic clips.Combination managements of acid suppression,gastrointestinal decompression and intravenous antibiotics were applied in all patients.Pathology reports confirmed complete resection of all lesions, with 0.5 to 3.7 cm in diameter.Normal diet was restored in 44 patients 48 ～ 72 h after the procedure.Pneumoperitoneum and focal peritonitis occurred in 2 cases, one of which underwent rupture and was clamped again.The 2 patients recovered after 10-12 days of conservative treatments.Follow-up endoscopy revealed white ulcerous scar in all cases.Conclusion Endoscopic resection and closure therapy is a safe, economic and less invasive treatment for non-intraluminal gastric stromal tumors originating from the muscularis propria layer.
